NIH: Office of Disease Prevention

Medicine: Mind the Gap

Stepped Wedge Cluster Randomized Designs for Disease Prevention Research

Monica Taljaard, Ph.D.

July 11, 2018
11:00 a.m.–12:00 noon ET

Monica Taljaard, Ph.D. External Website Policy
Senior Scientist, Clinical Epidemiology Program
Professor, Ottawa Hospital Research Institute
Associate Professor, School of Epidemiology and Public Health
University of Ottawa

Registration External Website Policy is required for this webinar. You will receive a confirmation email that contains detailed information about joining the webinar.

About the Webinar

The stepped wedge cluster randomized design has seen a rapid increase in popularity over the past decade. The stepped wedge is different than the conventional parallel arm cluster randomized design in that all clusters (e.g., communities, schools, or hospitals), rather than only half, receive the intervention. Furthermore, the order in which they receive the intervention is determined at random, and outcomes are repeatedly observed both before and after implementation of the intervention. The stepped wedge has numerous methodological complexities that need to be considered in its design, analysis, and reporting. This presentation will explain the unique characteristics of the stepped wedge cluster randomized design and its implications for sample size calculation and analysis, and discuss its strengths and weaknesses compared to traditional designs. Emphasis will be on application, with examples in disease prevention and health promotion research.

About Monica Taljaard, Ph.D.

Monica Taljaard, Ph.D., is a Senior Scientist in the Clinical Epidemiology Program at the Ottawa Hospital Research Institute (OHRI) and Associate Professor in the School of Epidemiology and Public Health at the University of Ottawa. She has a Ph.D. in Epidemiology and Biostatistics from Western University, and her main research interests are in the design, analysis, and ethics of cluster randomized trials. As a methodologist with the Ottawa Methods Centre, Dr. Taljaard works with clinicians and researchers from a variety of disciplines and medical specialties in the design and analysis of cluster randomized trials, standard clinical trials, and observational studies. She also supervises M.Sc. and Ph.D. students in Epidemiology and teaches Biostatistics courses at the University of Ottawa.

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